-研究成果
[1]. Yongqiang Sha, Huhai Hong, Wenjie Cai*, Tao Sun*. Single-Cell Transcriptomics of Endothelial Cells in Upper and Lower Human Esophageal Squamous Cell Carcinoma. Current Oncology. 2022. 29: 7680-7694.
[2]. Yongqiang Sha*, Beibei Zhang, Liping Chen, Chunli Wang, Tao Sun*. Dehydrocorydaline Accelerates Cell Proliferation and Extracellular Matrix Synthesis of TNFα-Treated Human Chondrocytes by Targeting Cox2 through JAK1-STAT3 Signaling Pathway. Int J Mol Sci. 2022; 23 (13):7268.
[3]. Yongqiang Sha*, Beibei Zhang, Liping Chen, Huhai Hong, Qingjia Chi. Mechano Growth Factor Accelerates ACL Repair and Improves Cell Mobility of Mechanically Injured Human ACL Fibroblasts by Targeting Rac1-PAK1/2 and RhoA-ROCK1 Pathways. Int J Mol Sci. 2022, 23(8): 4331.
[4]. Yongqiang Sha; Wenjie Cai; Alani mohanad Khalid; Qingjia Chi; Jing Wang; Tao Sun; Chunli Wang. Pretreatment with mechano growth factor E peptide attenuates osteoarthritis through improving cell proliferation and extracellular matrix synthesis in chondrocytes under severe hypoxia. International Immunopharmacology, 2021, 97: 107628.
[5]. Sha Y, Yang L, Lv Y*. MGF E peptide improves ACL repair by inhibiting hypoxia-induced cell apoptosis and accelerating angiogenesis. J Cell Physiol. 2019. 234: 8846-8861.
[6]. Sha Y, Xu Z, Yang L, Lv Y*. ERK1/2 and Akt phosphorylation were essential for MGF E peptide regulating cell morphology and mobility but not proangiogenic capacity of BMSCs under severe hypoxia. Cell Biochem Funct. 2018. 36:155-165.
[7]. Sha Y, Afandi R, Zhang B, Yang L, Lv Y*. MGF E peptide pretreatment improves collagen synthesis and cell proliferation of injured human ACL fibroblasts via MEK-ERK1/2 signaling pathway. Growth Factors. 2017. 35:29-38.
[8]. Sha Y, Lv Y*, Xu Z, Yang L, Hao X, Afandi R. MGF E peptide pretreatment improves the proliferation and osteogenic differentiation of BMSCs via MEK-ERK1/2 and PI3K-Akt pathway under severe hypoxia. Life Sci. 2017. 189:52-62.
[9]. Y Sha, Y Lv*. Effects of MGF E peptide pretreatment on the cell morphology, mobility, proliferation and osteogenic differentiation of BMSCs under severe hypoxia. FEBS J. 2017. 284 (Special Issue, meeting abstract): 126-126.
[10]. 沙永强, 杨力, 吕永钢*.力生长因子E肽对前交叉韧带成纤维细胞活力、迁移和侵袭的影响. 医用生物力学, 2016. 31:227-234.
[11]. Jing Wang, Yongqiang Sha, Tao Sun. m6A modifications play crucial roles in glial cell development and brain tumorigenesis. Front Oncol, 2021, 11: 611660.
[12]. Yuan Yu; Zhiwei Zeng; Danlin Xie; Renliang Chen; Yongqiang Sha; Shiying Huang; Wenjie Cai; Wanhua Chen; Wenjun Li; Rongqin Ke; Tao Sun. Interneuron origin and molecular diversity in the human fetal brain. Nature Neuroscience, 2021, 24: 1745-1756.
[13]. Chunli Wang; Yongqiang Sha; Qingjia Chi; Kang Xu; Sixiang Wang; Li Yang; K L Paul Sung. LOX suppresses the inflammatory response in ACL fibroblasts and promotes tissue regeneration by targeting myotrophin via the nuclear-kappa B pathway. Journal of tissue engineering and regenerative medicine, 2020. 14: 1063-1076.
[14]. Chunli Wang; Qingjia Chi; Yongqiang Sha; Kang Xu; Chunming Xu; Cheng Chen; Wei Huang; Peixing Chen; Peter Chen; Li Yang, K. L. Paul Sung. Mechanical injury and IL-1β regulated LOXs and MMP-1, 2, 3 expression in ACL fibroblasts co-cultured with synoviocytes. Biotechnology Letters, 2020. 42: 1567-1579.
[15]. Xu K, Sha Y, Wang S, Chi Q, Liu Y, Wang C, Yang L. Effects of Bakuchiol on chondrocyte proliferation via the PI3K-Akt and ERK1/2 pathways mediated by the estrogen receptor for promotion of the regeneration of knee articular cartilage defects. Cell Prolif. 2019. 52(5): e12666.
[16]. Wang C, Al-Ani MK, Sha Y, Chi Q, Dong N, Yang L, Xu K. Psoralen Protects Chondrocytes, Exhibits Anti-Inflammatory Effects on Synoviocytes, and Attenuates Monosodium Iodoacetate-Induced Osteoarthritis. Int J Biol Sci. 2019. 15: 229-238.
[17]. He J, Dong L, Xu K, Qian Y, Wang C, Sha Y, et al. Mechano growth factor E peptide inhibits invasion of melanoma cells and up-regulates CHOP expression via endoplasmic reticulum stress. Biotechnol Lett. 2018. 40:205-213.
[18]. Xu K, Sun Y, Mohanad KA, Wang C, Sha Y, et al. Synergistic promoting effects of bone morphogenetic protein 12/connective tissue growth factor on functional differentiation of tendon derived stem cells and patellar tendon window defect regeneration. J Biomech. 2017. 66:95-102.
[19]. Lv Y*, Nan P, Chen G, Sha Y, Xia B, Yang L. In vivo repair of rat transected sciatic nerve by low-intensity pulsed ultrasound and induced pluripotent stem cells-derived neural crest stem cells. Biotechnol Lett. 2015. 37:2497-506.
[20]. 余璨,沙永强,郭盼,陈义梅,等.力生长因子对软组织修复调控作用的研究.生物医学工程学杂志.2015. 32:235-9.
[21]. Lv Y*, Hao X, Sha Y, Yang L. Pretreatment with mechano-growth factor E peptide protects bone marrow mesenchymal cells against damage by fluid shear stress. Biotechnol Lett. 2014. 36:2559-69.
[22]. Lv Y*, Zhao P, Chen G, Sha Y, Yang L. Effects of low-intensity pulsed ultrasound on cell viability, proliferation and neural differentiation of induced pluripotent stem cells-derived neural crest stem cells. Biotechnol Lett. 2013. 35:2201-2212.
