林俊生 教授

电子邮箱:junshenglin@hqu.edu.cn / junshenglin3@hotmail.com

-TERTIARY EDUCATION

1994-1997 PhD in Biology

The University of Auckland, New Zealand

1990-1991 Diploma in Business Management

Regent Business College, Australia

1978-1983 Bachelor of Medicine

Fujian Medical University (FMU), China

-EMPLOYMENT RECORD

2012- Present Professor

School of Biomedical Sciences

Huqiao University, China

2012- Present Adjunct Professor

School of Biological Sciences

Victoria University of Wellington

2001-2012 Scientist, and then Senior Scientist

Wallaceville/Invermay

AgResearch

New Zealand

1997-2000 Postdoctoral, and then Acadamic Research Fellow

The School of Medicine

The University of Auckland, New Zealand

1991-1993 Resident Medical Officer

Royal Prince Alfred Hospital, Sydney, Australia

1983-1989 Resident Doctor, and then Chief Resident Doctor

The First Affiliated Hospital of FMU, China

-​Reserch intersts

基于核酸分子的诊断试剂和药物开发

干细胞基础和临床研究

代血清的应用研究

强直性脊柱炎

虚拟仿真的影像处理

重组蛋白

-SELECTED PUBLICATIONS (in current 4 years)

Peer-reviewed papers

1. Chen Y, Lin J*, The application of aptamer in apoptosis, Biochimie (2016), doi: 10.1016 /j.biochi.2016.10.008.

2. SU X, HE Y, LIN J*, Comparative analysis of detection methods for dissociated adsorption between aptamer and protein, Transducer and Microsystem Technologies, 2016 accepted

3. Lin JS*, Kauff A, Diao Y, Yang HY, Lawrence S and Juengel J, Creation of DNA aptamers against recombinant BMP15, REPROD FERT DEVELOP 2016, 28(8) 1164-1171. doi: 10.1071/RD14409

4. Sun A, Lin J, Chao P, et al. Biological Evaluation of Ferrocenyl Olefins: Cancer Cell Growth Inhibition, ROS Production, and Apoptosis Activity[J]. Febs Letters, 2016, 100(1):81-4.

5. Wen YG, Yu H, Lin JS*, Advanced technology in semen stain identification, National Journal of Andrology, 2016, 22(6): 553-558

6. Su X, He Y, Lin J* Comparative analysis of detection methods for dissociated adsorption between aptamer and protein, Transducer and Microsystem Technologies, 2016 accepted

7. Huang X, Wang X, Lv Y, Xu L, Lin JS*, Diao Y, Protection Effect of Kallistatin on Carbon Tetrachloride-Induced Liver Fibrosis in Rats via Antioxidative Stress. PLoS ONE 2014, 9 (2), e88498

8. Sun A, Xu X, Lin J, Cui X and Xu R, Neuroprotection by Saponins, Phytotherapy Research 2015 Feb;29(2):187-200

9. Wang F, Lin J, Xu R, The Molecular Mechanisms of TRAIL Resistance in Cancer Cells: Help in Designing New Drugs, Curr Pharm Des. 2014;20(42):6714-22.

10. Huang KF, Huang XP, Xiao GQ, Yang HY, Lin JS*, Diao Y, Kallistatin, a novel anti-angiogenesis agent, inhibits angiogenesis via inhibition of the NF-κB signaling pathway, Biomed Pharmacother. 2014 May;68(4):455-61

11. Huang KF, Yang HY, Xing YM, Lin JS *, Diao Y*, Recombinant human kallistatin inhibits angiogenesis by blocking VEGF signaling pathway, J Cell Biochem. 2014 Mar;115(3):575-84

12. Pang SQ, Wang GQ, Lin JS, Diao Y, Xua RA, Cytotoxic activity of the alkaloids from Broussonetia papyrifera fruits, Pharmaceutical Biology 2014 Oct, 52(10):1315-9

13. Diao Y, Zhao XF, Lin JS, Wang QZ, Xu RA: Protection of the liver against CCl(4)-induced injury by intramuscular electrotransfer of a kallistatin-encoding plasmid. World J Gastroenterol 2011, 17:111-117.

14. Lin JS, McNatty KP: Aptamer-Based Regionally Protected PCR for Protein Detection. Clin Chem 2009, 55:1686-1693.

15. Lin J-M, Callon KE, Lin J-S, Watson M, Empson V, Tong PC, Grey A, Naot D, Green CR, Reid IR, Cornish J: Actions of fibroblast growth factor-8 in bone cells in vitro. American Journal of Physiology - Endocrinology And Metabolism 2009, 297:E142-E150.

16. Lin JM, Callon KE, Lin JS, Watson M, Empson V, Grey A, Naot D, Green CR, Reid IR, Cornish J: Skeletal actions of fibroblast growth factor-8 in vitro. Bone 2009, 44:S135-S135.

17. FENG, Jing-xian, WANG' Jia-wen, Jun-sheng LIN, and Yong DIAO. "Ribozyme Riboswitch Based Gene Expression Regulation Systems for Gene Therapy Applications: Progress and Challenges ". Acta Pharmaceutica Sinica 2014,49(11): 1504-11.

18. WANG, Jia-wen, Jing-xian FENG, Jun-sheng LIN, and Yong DIAO. "The Artificial Aptazyme Based Riboswitch." China Biotechnology 34, no. 2 (2014): 59-64.

19. YANG, Chun-xue, Xiao-ping HUANG, Jun-sheng LIN, and Yong DIAO. "Manufacture and Quality Control of Follicle Stimulating Hormone Products." Chin Pharm J 49, no. 7 (2014): 529-33.

20. Huang, Xiaoping , Xiao Wang, Chunxue Yang, Dongfang Jia, Junsheng Lin, and Yong Diao. "Expression of Human Long-Acting Fsh in Cho Cell and Its Bioactivity in Vivo ". Chinese Journal of Biotechnology 30, no. 6 (2014): 954-61.

21. JIA, Dong-fang, Jun-sheng LIN, and Yong DIAO. "Novel Targets for Antibiotics Discovery: Riboswitches." Acta Pharmaceutica Sinica 48, no. 9 (2013): 1361-68.

22. ZHU, Yao, Ying-hui LÜ, Hui-yong YANG, Jun-sheng LIN, and Qi-zhao WANG. "Recent Progress of the Aptamer-Based Antiviral Drugs." Acta Pharmaceutica Sinica 48, no. 4 (2013): 447-56.

23. SHI, Lei, Huiyong, YANG, Junsheng LIN, and Yong DIAO. "Thermodynamic or Kinetic Control of Riboswitch-Mediated Gene Expression." Chinese Journal of Biochemical Pharmaceutics 33, no. 4 (2012): 509-11.

24. Yang, Huiyong, Yong Diao, Junsheng Lin, and Ruian Xu. "Engineering and Screening of Artificial Riboswitch as a Novel Gene Control Element." Chinese Journal of Biotechnology 28, no. 2 (2012): 135-43.

25. DIAO, Yong, and Jun-sheng LIN. "The Molecular Design and Drug Development of Recombinant Long-Acting Follicle Stimulating Hormone ". Acta Pharmaceutica Sinica 47, no. 4 (2012): 421-26.

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